The researchers at the University of Chicago Medical Center took this opportunity to explore what other information could be collected to help in developing more anti viral drugs to withstand the flu virus. The researchers were amazingly able to develop their own genetic screening tool to that allowed them to clearly identify factors that allow the flu virus to infect a person's lung cells. By exposing the cells to the H5N1, commonly known as bird flu, two genes stood out as having similar properties in common among one another. The first gene was SLC35A1, which encodes for a protein to develop a receptor for the flu on the cell, which is extremely important considering if this gene did not exist, the flu would have no attachment point. The other gene is called CIC, which helps shut-down the cell's immune system to foreign invaders, like the flu. This specific gene was a very interesting find, as this gene is located in the host's body, and helps foreign viruses like the flu, open access into our body's cells. This is a very important finding that the researchers were able to conduct and pinpoint two genes that aid in the flu virus's attack, because by knowing this, future anti viral drugs can be developed to disrupt these passageways, and thus preventing H5N1 or any other virus from getting into our body. In my opinion, there needs to be further research done on this topic, on these specific genes, because knowing that CIC and SLC35A1 provide a latch and passageway to the cell, is the first step in finding out how to develop a drug from the current available drugs we have to stop the connection from occurring.
For more information on this article: https://www.sciencedaily.com/releases/2018/04/180411111115.htm
For information on the University of Chicago Medical Center's programs and medical research: http://www.uchospitals.edu/index.shtml
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