Correcting Duchenne Muscular Dystrophy
The article "CRISPR Corrects Duchenne-Causing Mutations" discusses the research done using gene editing to treat a genetic disease. Duchenne Muscular Dystophy, DMD, is a X-linked disease that is fatal. Individuals with DMD have weakened skeletal systems and heart muscles which progressively get worse throughout their lives. Researchers have been studying a gene editing system for years called CRISPR-Cpf1. In a study at the University of Texas Southwestern Medical Center researchers found that this gene editing system reversed the effects of DMD. They took human stem cells and put them in a mouse model. After injecting the modified genes in the parents, the offspring of the genetically edited mice were noted to be stronger and had normal skeletal, muscle, heart and brain tissue. With this research, gene editing can be used to treat many fatal genetic diseases in the future.