Tuesday, March 28, 2017
Study finds Brain Tumor Associated with Genetic Error
Just in the United States, hundreds of thousands of people suffer from brain tumors. More than 20% of these cases are malignant tumors that spread quickly and result in a very low patient survival rate, amongst the 34 percentile. A study done by international researchers from the United Kingdom, United States, and other European countries have identified 13 new genetic errors that correlate with high risk of glioma, a type of brain tumor that arises from the glial cells. This type of brain tumor causes 13,000 deaths per year alone, however little is known about what factors contribute to contracting a glioma. The test was run with thousands of patients diagnosed with these brain tumors and thousands of healthy, glioma-free patients as the control group. The study shows that these genetic errors impact various cell functions, including the genesis and division of neurons, cell cycle regulation, DNA repair, and the production of some proteins which all contribute to the generation of theses tumors inside the brain.
This study has proven to give researchers and doctors a greater understanding of how glioma tumors form. With more research these scientist will be able to find even more genetic strands that affect a person's chances. Understanding more about gliomas gives insight about ways of identifying people at high inherited risk and will open up a search for new treatments. The number of genetic variants identified after this research was 13, with new research being conducted, this number has doubled.
Tags: Brain tumor, cancer, genetic linkage, cell growth